Mouse Model of Fracture Pain
نویسندگان
چکیده
منابع مشابه
A fracture pain model in the rat: adaptation of a closed femur fracture model to study skeletal pain.
BACKGROUND Because of the relative lack of understanding of the mechanisms that drive skeletal pain, the purpose of this study was to adapt a previously validated closed femur fracture model to quantitatively evaluate skeletal pain in female and male rats. METHODS Three-month-old female and male Sprague-Dawley rats were anesthetized, and a stainless steel pin was inserted into the intramedull...
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BACKGROUND Thrombin related peptide (TP508) is a 23 amino-acid synthetic peptide that represents a portion of the receptor-binding domain of thrombin molecule. Previous studies have shown that TP508 can accelerate musculoskeletal tissue repair including fracture healing. OBJECTIVES The aim of this study was to investigate the effect of TP508 on fracture healing in a murine fracture model repr...
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Background: Thrombin related peptide (TP508) is a 23 amino-acid synthetic peptide that represents a portion of the receptor-binding domain of thrombin molecule. Previous studies have shown that TP508 can accelerate musculoskeletal tissue repair including fracture healing. Objectives: The aim of this study was to investigate the effect of TP508 on fracture healing in a murine fracture model repr...
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ژورنال
عنوان ژورنال: Anesthesiology
سال: 2008
ISSN: 0003-3022
DOI: 10.1097/aln.0b013e3181649333